InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mrpl14

Summary

InnateDB Protein

IDBP-185811.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mrpl14

Protein Name

mitochondrial ribosomal protein L14

Synonyms

1110006I11Rik; AI846816; MRP-L32; Rpml32;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000024734

InnateDB Gene

IDBG-185809 (Mrpl14)

Protein Structure

UniProt Annotation

Function

May form part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1, intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003735	structural constituent of ribosome
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006412

translation

Cellular Component

GO:0005739	mitochondrion
GO:0005840	ribosome

Protein Structure and Domains

PDB ID

MGI:1333864

InterPro

IPR000218 Ribosomal protein L14b/L23e
IPR023571 Ribosomal protein L14 domain

PFAM

PF00238

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D1I6

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

68463

UniGene

RefSeq

NP_081008

MGI ID

MGI Symbol

Mrpl14

OMIM

CCDS

CCDS28815

HPRD

IMGT

EMBL

AK003500 AK050273 AK144153 BC027021

GenPept

AAH27021 BAB22824 BAC34158 BAE25734