InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rsph9

Summary

InnateDB Protein

IDBP-186001.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rsph9

Protein Name

radial spoke head 9 homolog (Chlamydomonas)

Synonyms

1700027N10Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000024762

InnateDB Gene

IDBG-185999 (Rsph9)

Protein Structure

UniProt Annotation

Function

Probable component of the axonemal radial spoke head (By similarity). Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules. {ECO:0000250}.

Subcellular Localization

Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000305}. Note=Radial spoke. {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed in the embryonic node at E7.5 and in the nasal, lung, tracheal and brain ventricle epithelium at E18.5- E19.5. {ECO:0000269PubMed:19200523}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0003341	cilium movement
GO:0035082	axoneme assembly

Cellular Component

GO:0005856	cytoskeleton
GO:0005930	axoneme
GO:0031514	motile cilium

Protein Structure and Domains

PDB ID

MGI:1922814

InterPro

IPR006802 Radial spokehead-like protein

PFAM

PF04712

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D9V4

PhosphoSite

PhosphoSite-

TrEMBL

Q3TMP7

UniProt Splice Variant

Entrez Gene

75564

UniGene

RefSeq

NP_083614

MGI ID

MGI Symbol

Rsph9

OMIM

CCDS

CCDS28820

HPRD

IMGT

EMBL

AK006440 AK165820 BC019423

GenPept

AAH19423 BAB24590 BAE38394