InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gstm1

Summary

InnateDB Protein

IDBP-186033.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gstm1

Protein Name

glutathione S-transferase, mu 1

Synonyms

Gstb-1; Gstb1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000004140

InnateDB Gene

IDBG-186031 (Gstm1)

Protein Structure

UniProt Annotation

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004364	glutathione transferase activity
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0008152	metabolic process
GO:0035690	cellular response to drug

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:95860

InterPro

IPR003081 Glutathione S-transferase, Mu class
IPR004045 Glutathione S-transferase, N-terminal
IPR004046 Glutathione S-transferase, C-terminal
IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold

PFAM