InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gcm1

Summary

InnateDB Protein

IDBP-186153.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gcm1

Protein Name

glial cells missing homolog 1 (Drosophila)

Synonyms

Gcm-rs2; Gcm1-rs1; GCMa; glide;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000024104

InnateDB Gene

IDBG-186151 (Gcm1)

Protein Structure

UniProt Annotation

Function

Transcription factor that is necessary for placental development. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00245}.

Disease Associations

Tissue Specificity

Placenta specific. {ECO:0000269PubMed:8814290}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0008270	zinc ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060018	astrocyte fate commitment
GO:0060143	positive regulation of syncytium formation by plasma membrane fusion
GO:0060670	branching involved in labyrinthine layer morphogenesis
GO:0060706	cell differentiation involved in embryonic placenta development