Mus musculus Protein: Saa4 | |||||
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Summary | |||||
InnateDB Protein | IDBP-186370.6 | ||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
Gene Symbol | Saa4 | ||||
Protein Name | serum amyloid A 4 | ||||
Synonyms | Saa-4; Saa-5; | ||||
Species | Mus musculus | ||||
Ensembl Protein | ENSMUSP00000006952 | ||||
InnateDB Gene | IDBG-186368 (Saa4) | ||||
Protein Structure | |||||
UniProt Annotation | |||||
Function | Major acute phase reactant. Apolipoprotein of the HDL complex. | ||||
Subcellular Localization | Secreted. | ||||
Disease Associations | Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. | ||||
Tissue Specificity | Expressed by the liver; secreted in plasma. | ||||
Comments | |||||
Interactions | |||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||
PDB ID | MGI:98224 | ||||
InterPro |
IPR000096
Serum amyloid A protein |
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PFAM |
PF00277
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PRINTS |
PR00306
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PIRSF |
PIRSF002472
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SMART |
SM00197
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TIGRFAMs | |||||
Post-translational Modifications | |||||
Modification | |||||
Cross-References | |||||
SwissProt | P31532 | ||||
PhosphoSite | PhosphoSite- | ||||
TrEMBL | |||||
UniProt Splice Variant | |||||
Entrez Gene | 20211 | ||||
UniGene | Mm.394591 | ||||
RefSeq | NP_035446 | ||||
MGI ID | |||||
MGI Symbol | Saa4 | ||||
OMIM | |||||
CCDS | CCDS21283 | ||||
HPRD | |||||
IMGT | |||||
EMBL | BC019212 U02554 U40397 U65403 | ||||
GenPept | AAA17564 AAB17555 AAC52904 AAH19212 | ||||