Mus musculus Protein: Saa4
Summary
InnateDB Protein IDBP-186370.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Saa4
Protein Name serum amyloid A 4
Synonyms Saa-4; Saa-5;
Species Mus musculus
Ensembl Protein ENSMUSP00000006952
InnateDB Gene IDBG-186368 (Saa4)
Protein Structure
UniProt Annotation
Function Major acute phase reactant. Apolipoprotein of the HDL complex.
Subcellular Localization Secreted.
Disease Associations Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
Tissue Specificity Expressed by the liver; secreted in plasma.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006953 acute-phase response
Cellular Component
GO:0005576 extracellular region
GO:0034364 high-density lipoprotein particle
Protein Structure and Domains
PDB ID MGI:98224
InterPro IPR000096 Serum amyloid A protein
PFAM PF00277
PRINTS PR00306
PIRSF PIRSF002472
SMART SM00197
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P31532
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 20211
UniGene Mm.394591
RefSeq NP_035446
MGI ID
MGI Symbol Saa4
OMIM
CCDS CCDS21283
HPRD
IMGT
EMBL BC019212 U02554 U40397 U65403
GenPept AAA17564 AAB17555 AAC52904 AAH19212