Version 5.4
Mus musculus Protein: Ces3a
Summary
InnateDB Protein IDBP-186489.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ces3a
Protein Name carboxylesterase 3A
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000090911
InnateDB Gene IDBG-186487 (Ces3a)
Protein Structure
UniProt Annotation
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs.
Subcellular Localization Endoplasmic reticulum lumen. Note=Microsomal membrane, lumen of endoplasmic reticulum.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0052689 carboxylic ester hydrolase activity
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005788 endoplasmic reticulum lumen
Protein Structure and Domains
PDB ID MGI:102773
InterPro IPR002018 Carboxylesterase, type B
IPR013094 Alpha/beta hydrolase fold-3
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00135
PF07859
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q63880
PhosphoSite PhosphoSite-Q63880
TrEMBL
UniProt Splice Variant
Entrez Gene 382053
UniGene Mm.295534
RefSeq NP_001158153
MGI ID
MGI Symbol Ces3a
OMIM
CCDS CCDS52652
HPRD
IMGT
EMBL AK138932 AK149499 BC048380 BC057187 BC057188 BC061004 S64130
GenPept AAB27606 AAH48380 AAH57187 AAH57188 AAH61004 BAE23821 BAE28921

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca