Version 5.4
Mus musculus Protein: Krt6a
Summary
InnateDB Protein IDBP-186497.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Krt6a
Protein Name keratin 6A
Synonyms 2310016L08Rik; Krt2-6a; Krt2-6c; mK6[a]; MK6a;
Species Mus musculus
Ensembl Protein ENSMUSP00000023788
InnateDB Gene IDBG-186495 (Krt6a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Predominates in the adult trunk skin, tongue, trachea/esophagus and eye. In adult skin, localization is restricted to hair follicles, where it is localized predominantly in the outer root sheath. {ECO:0000269PubMed:9790766}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
GO:0002009 morphogenesis of an epithelium
GO:0016055 Wnt signaling pathway
GO:0031424 keratinization
GO:0045109 intermediate filament organization
Cellular Component
GO:0005882 intermediate filament
GO:0045095 keratin filament
Protein Structure and Domains
PDB ID MGI:1100845
InterPro IPR001664 Intermediate filament protein
IPR003054 Keratin, type II
IPR009053 Prefoldin
PFAM PF00038
PRINTS PR01276
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P50446
PhosphoSite PhosphoSite-P50446
TrEMBL Q9CV13
UniProt Splice Variant
Entrez Gene 16687
UniGene Mm.403409
RefSeq NP_032502
MGI ID
MGI Symbol Krt6a
OMIM
CCDS CCDS27860
HPRD
IMGT
EMBL AB012033 AK010039 BC080820 K02108
GenPept AAA39395 AAH80820 BAA34178 BAB26659

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca