InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ces3b

Summary

InnateDB Protein

IDBP-186612.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ces3b

Protein Name

carboxylesterase 3B

Synonyms

Ces31L; Ces3L; EG13909; Es31; ES31L; Gm4738;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000090909

InnateDB Gene

IDBG-186608 (Ces3b)

Protein Structure

UniProt Annotation

Function

Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum lumen {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016787	hydrolase activity
GO:0052689	carboxylic ester hydrolase activity

Biological Process

GO:0008150	biological_process
GO:0008152	metabolic process

Cellular Component

GO:0005788

endoplasmic reticulum lumen

Protein Structure and Domains

PDB ID

MGI:3644960

InterPro

IPR002018 Carboxylesterase, type B
IPR013094 Alpha/beta hydrolase fold-3
IPR029058 Alpha/Beta hydrolase fold

PFAM

PF00135
PF07859

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8VCU1

PhosphoSite

PhosphoSite-Q8VCU1

TrEMBL

UniProt Splice Variant

Entrez Gene

13909

UniGene

Mm.482444

RefSeq

NP_653094

MGI ID

MGI Symbol

Ces3b

OMIM

CCDS

CCDS22590

HPRD

IMGT

EMBL

AC164311 BC010812 BC019147 CH466525

GenPept

AAH10812 AAH19147 EDL11245 EDL11246