InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ooep

Summary

InnateDB Protein

IDBP-186708.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ooep

Protein Name

oocyte expressed protein homolog (dog)

Synonyms

2410146L05Rik; Floped; Moep19; Sddr;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034900

InnateDB Gene

IDBG-186706 (Ooep)

Protein Structure

UniProt Annotation

Function

As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions. {ECO:0000269PubMed:18804437}.

Subcellular Localization

Cytoplasm. Note=In the subcortical cytoplasm of early embryos from the 1-cell to the blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact regions.

Disease Associations

Tissue Specificity

Expressed in ovaries, where it is restricted to growing oocytes, with greatest levels in fully grown oocytes. {ECO:0000269PubMed:18804437}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding

Biological Process

GO:0001701	in utero embryonic development
GO:0006468	protein phosphorylation
GO:0007566	embryo implantation
GO:0009566	fertilization
GO:0009880	embryonic pattern specification
GO:0035088	establishment or maintenance of apical/basal cell polarity
GO:0043623	cellular protein complex assembly