Version 5.4
Mus musculus Protein: Dzip1
Summary
InnateDB Protein IDBP-186802.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dzip1
Protein Name DAZ interacting protein 1
Synonyms 2510025K24Rik; 2810422M04Rik; mKIAA0996;
Species Mus musculus
Ensembl Protein ENSMUSP00000004055
InnateDB Gene IDBG-186798 (Dzip1)
Protein Structure
UniProt Annotation
Function May participate in spermatogenesis via its interaction with DAZ. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000269PubMed:15081113}. Cytoplasm {ECO:0000269PubMed:15081113}. Note=In primary and secondary spermatocytes, it is predominantly cytoplasmic. Colocalizes with DAZL in primordial germ cells. In spermatocytes, it localizes to a unique U-shaped pattern in cytoplasm.
Disease Associations
Tissue Specificity Expressed in testis and undifferentiated ES cells. {ECO:0000269PubMed:15081113}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0030154 cell differentiation
GO:0042384 cilium assembly
Cellular Component
GO:0005634 nucleus
GO:0005814 centriole
GO:0036064 ciliary basal body
Protein Structure and Domains
PDB ID MGI:1914311
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BMD2
PhosphoSite PhosphoSite-Q8BMD2
TrEMBL Q6PAU2
UniProt Splice Variant
Entrez Gene 66573
UniGene
RefSeq XP_006519450
MGI ID
MGI Symbol Dzip1
OMIM
CCDS CCDS37011
HPRD
IMGT
EMBL AK021163 AK032834 AK129256 BC060051 BC098211
GenPept AAH60051 AAH98211 BAB32310 BAC28050 BAC98066

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca