Version 5.4
Mus musculus Protein: Mki67ip
Summary
InnateDB Protein IDBP-186815.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mki67ip
Protein Name Mki67 (FHA domain) interacting nucleolar phosphoprotein
Synonyms AI852665; C130020J04Rik; Mki67ip;
Species Mus musculus
Ensembl Protein ENSMUSP00000027626
InnateDB Gene IDBG-186813 (Mki67ip)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus, nucleolus. Chromosome {ECO:0000250}. Note=Localizes to mitotic chromosomes in conjunction with MKI67. {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in brain, heart, hind limb muscles, intestine, liver, skin and spleen. {ECO:0000269PubMed:12798774}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0010923 negative regulation of phosphatase activity
Cellular Component
GO:0000794 condensed nuclear chromosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1915199
InterPro IPR000504 RNA recognition motif domain
IPR021043 MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding
PFAM PF00076
PF12196
PRINTS
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91VE6
PhosphoSite PhosphoSite-Q91VE6
TrEMBL Q8BMY3
UniProt Splice Variant
Entrez Gene 67949
UniGene Mm.397262
RefSeq NP_080748
MGI ID
MGI Symbol Nifk
OMIM
CCDS CCDS15222
HPRD
IMGT
EMBL AB056870 AK011340 AK019209 AK077770 AY030275 BC058559
GenPept AAH58559 AAK38160 BAB61920 BAC25329 BAC25583 BAC36999

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca