InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Krt4

Summary

InnateDB Protein

IDBP-187193.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Krt4

Protein Name

keratin 4

Synonyms

AW108092; K4; Krt-2.4; Krt2-4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023797

InnateDB Gene

IDBG-187191 (Krt4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed in the dorsal and ventral epithelium of the tongue. Highest expression levels are detected in the suprabasal layer with low levels detected in the basal cell layer. Within the suprabasal layer expression is highest in the spinous cells, decreases in the granular cells and is not detected in the stratum corneum. {ECO:0000269PubMed:2418416}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0007010	cytoskeleton organization
GO:0009790	embryo development
GO:0030855	epithelial cell differentiation
GO:0050680	negative regulation of epithelial cell proliferation