Version 5.4
Mus musculus Protein: Oxgr1
Summary
InnateDB Protein IDBP-187327.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Oxgr1
Protein Name oxoglutarate (alpha-ketoglutarate) receptor 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000055137
InnateDB Gene IDBG-187325 (Oxgr1)
Protein Structure
UniProt Annotation
Function Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway. {ECO:0000269PubMed:15141213}.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Predominanltly expressed in the kidney with limited expression in the testis and the smooth muscle. {ECO:0000269PubMed:15141213}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001609 G-protein coupled adenosine receptor activity
GO:0001883 purine nucleoside binding
GO:0004930 G-protein coupled receptor activity
GO:0016208 AMP binding
Biological Process
GO:0001973 adenosine receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2685145
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6IYF8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 239283
UniGene Mm.138520
RefSeq NP_001001490
MGI ID
MGI Symbol Oxgr1
OMIM
CCDS CCDS27340
HPRD
IMGT
EMBL AK142510 AY612852 BC119196 BC119200
GenPept AAI19197 AAI19201 AAT10591 BAE25093

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca