Version 5.4
Mus musculus Protein: 5330417C22Rik
Summary
InnateDB Protein IDBP-187477.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol 5330417C22Rik
Protein Name RIKEN cDNA 5330417C22 gene
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000040128
InnateDB Gene IDBG-187475 (5330417C22Rik)
Protein Structure
UniProt Annotation
Function May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Late endosome membrane {ECO:0000250}; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein. Lysosome membrane {ECO:0000250}; Single- pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0016236 macroautophagy
GO:2000786 positive regulation of autophagic vacuole assembly
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Cellular Component
GO:0005765 lysosomal membrane
GO:0005802 trans-Golgi network
GO:0005887 integral component of plasma membrane
GO:0031902 late endosome membrane
Protein Structure and Domains
PDB ID MGI:1923930
InterPro IPR009011 Mannose-6-phosphate receptor binding domain
IPR009030 Insulin-like growth factor binding protein, N-terminal
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2AFS3
PhosphoSite PhosphoSite-A2AFS3
TrEMBL
UniProt Splice Variant
Entrez Gene 229722
UniGene Mm.400506
RefSeq NP_001028476
MGI ID
MGI Symbol 5330417C22Rik
OMIM
CCDS CCDS17761
HPRD
IMGT
EMBL AK139330 AK173149 AL672200 AL683823 BC022655 BC051424
GenPept AAH22655 AAH51424 BAD32427 BAE23958 CAM14488 CAM14489 CAM22593 CAM22594

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca