Version 5.4
Mus musculus Protein: Mrgprb8
Summary
InnateDB Protein IDBP-187535.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrgprb8
Protein Name MAS-related GPR, member B8
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000052230
InnateDB Gene IDBG-187533 (Mrgprb8)
Protein Structure
UniProt Annotation
Function Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3033134
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019430 7TM GPCR, serpentine receptor class x (Srx)
PFAM PF00001
PF10328
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TN51
PhosphoSite PhosphoSite-Q7TN51
TrEMBL
UniProt Splice Variant
Entrez Gene 404240
UniGene Mm.357942
RefSeq NP_997422
MGI ID
MGI Symbol Mrgprb8
OMIM
CCDS CCDS21302
HPRD
IMGT
EMBL AY266419 BC138164 BC138165
GenPept AAI38165 AAI38166 AAP20071

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca