InnateDB Protein
|
IDBP-187657.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Tmed5
|
Protein Name
|
transmembrane emp24 protein transport domain containing 5
|
Synonyms
|
3110020O18Rik; 4432412D15Rik;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000002837
|
InnateDB Gene
|
IDBG-187653 (Tmed5)
|
Protein Structure
|
|
Function |
Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle- mediated retrograde transport (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus, cis-Golgi network membrane {ECO:0000250}; Single- pass type I membrane protein {ECO:0000250}. Endoplasmic reticulum- Golgi intermediate compartment membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Probably cycles between compartments of the early secretatory pathway. {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
1 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:1921586
|
InterPro |
IPR009038
GOLD
|
PFAM |
PF01105
PF13897
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q9CXE7
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
D3Z615
|
UniProt Splice Variant |
|
Entrez Gene |
73130
|
UniGene |
Mm.412524
|
RefSeq |
NP_083152
|
MGI ID |
|
MGI Symbol |
Tmed5
|
OMIM |
|
CCDS |
CCDS19508
|
HPRD |
|
IMGT |
|
EMBL |
AC134402
AC159996
AK014490
AK033463
AK170036
BC132023
BC138226
CH466529
|
GenPept |
AAI32024
AAI38227
BAB29390
BAC28301
BAE41524
EDL20134
|
|
|