Version 5.4
Homo sapiens Protein: TCL1B
Summary
InnateDB Protein IDBP-18766.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TCL1B
Protein Name T-cell leukemia/lymphoma 1B
Synonyms SYN-1; TML1;
Species Homo sapiens
Ensembl Protein ENSP00000343223
InnateDB Gene IDBG-244466 (TCL1B)
Protein Structure
UniProt Annotation
Function Enhances the phosphorylation and activation of AKT1 and AKT2. {ECO:0000269PubMed:10983986}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in a variety of tissues including placenta and testis. {ECO:0000269PubMed:10077617, ECO:0000269PubMed:10344735}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Protein Structure and Domains
PDB ID
InterPro IPR004832 TCL1/MTCP1
PFAM PF01840
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95988
PhosphoSite PhosphoSite-O95988
TrEMBL A0A024R6P4
UniProt Splice Variant
Entrez Gene 9623
UniGene Hs.632346
RefSeq NP_004909
HUGO HGNC:11649
OMIM 603769
CCDS CCDS32151
HPRD 04795
IMGT
EMBL AB018563 AB025274 AF110465 AF110466 AF137027 AL133467 BC041616 BC051000 CH471061 CR457087
GenPept AAD16996 AAD16997 AAD30130 AAH41616 AAH51000 BAA76712 BAA82476 CAG33368 EAW81619 EAW81620

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca