InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tmtc3

Summary

InnateDB Protein

IDBP-187958.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tmtc3

Protein Name

transmembrane and tetratricopeptide repeat containing 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000096921

InnateDB Gene

IDBG-187954 (Tmtc3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0009791	post-embryonic development
GO:0010468	regulation of gene expression
GO:0030154	cell differentiation
GO:0030324	lung development
GO:0048286	lung alveolus development
GO:0048747	muscle fiber development
GO:0060447	bud outgrowth involved in lung branching

Cellular Component

GO:0005575	cellular_component
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:3036255

InterPro

IPR001440 Tetratricopeptide TPR1
IPR013026 Tetratricopeptide repeat-containing domain
IPR013105 Tetratricopeptide TPR2
IPR013618 Domain of unknown function DUF1736
IPR019734 Tetratricopeptide repeat

PFAM

PF00515
PF07719
PF08409
PF13174
PF13176
PF13181

PRINTS

PIRSF

SMART

SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BRH0