InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fam65a

Summary

InnateDB Protein

IDBP-188006.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fam65a

Protein Name

family with sequence similarity 65, member A

Synonyms

2310066E14Rik; AI837433;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000039966

InnateDB Gene

IDBG-188004 (Fam65a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:17251388}. Note=Localizes to the podocyte major processes and cell body.

Disease Associations

Tissue Specificity

Expressed in the kidney exclusively by glomerular podocytes. {ECO:0000269PubMed:17251388}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005488	binding

Biological Process

GO:0007165	signal transduction
GO:0008150	biological_process

Cellular Component

GO:0005737	cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1922937

InterPro

IPR011072 HR1 rho-binding repeat
IPR016024 Armadillo-type fold

PFAM

PF02185

PRINTS

PIRSF

SMART

SM00742

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q68FE6

PhosphoSite

PhosphoSite-Q68FE6

TrEMBL

UniProt Splice Variant

Entrez Gene

75687

UniGene

Mm.41261

RefSeq

NP_001074710

MGI ID

MGI Symbol

Fam65a

OMIM

CCDS

CCDS52660

HPRD

IMGT

EMBL

AC127419 AK010063 AK122573 BC006820 BC030451 BC079880 CH466525

GenPept

AAH06820 AAH30451 AAH79880 BAB26677 BAC65855 EDL11288