Version 5.4
Mus musculus Protein: C1ql2
Summary
InnateDB Protein IDBP-188068.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C1ql2
Protein Name complement component 1, q subcomponent-like 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000037257
InnateDB Gene IDBG-188066 (C1ql2)
Protein Structure
UniProt Annotation
Function May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. {ECO:0000269PubMed:21262840}.
Subcellular Localization Secreted {ECO:0000269PubMed:18783346}.
Disease Associations
Tissue Specificity Highest expression in eye, followed by placenta and brain, intermediate expression in adipose tissue and lowest expression in lymph node and testis. {ECO:0000269PubMed:18783346}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0051259 protein oligomerization
Cellular Component
GO:0005576 extracellular region
GO:0005581 collagen trimer
Protein Structure and Domains
PDB ID MGI:3032521
InterPro IPR001073 Complement C1q protein
IPR008160 Collagen triple helix repeat
IPR008983 Tumour necrosis factor-like domain
PFAM PF00386
PF01391
PRINTS PR00007
PIRSF
SMART SM00110
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CFR0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 226359
UniGene Mm.337409
RefSeq NP_997116
MGI ID
MGI Symbol C1ql2
OMIM
CCDS CCDS15233
HPRD
IMGT
EMBL AK144471 BC040774 DQ002402
GenPept AAH40774 AAY21934 BAE25906

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca