Version 5.4
Mus musculus Protein: Cdca3
Summary
InnateDB Protein IDBP-188114.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdca3
Protein Name cell division cycle associated 3
Synonyms 2410005A12Rik; C8; Grcc8; Tome-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000024270
InnateDB Gene IDBG-188110 (Cdca3)
Protein Structure
UniProt Annotation
Function F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007067 mitotic nuclear division
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005575 cellular_component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:1315198
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99M54
PhosphoSite PhosphoSite-Q99M54
TrEMBL D3Z3H6
UniProt Splice Variant
Entrez Gene 14793
UniGene Mm.466190
RefSeq NP_038566
MGI ID
MGI Symbol Cdca3
OMIM
CCDS CCDS39629
HPRD
IMGT
EMBL AC002397 AC142254 AK008606 AK010409 AK011313 AK028159 AK145537 AK169792 BC002006 BC027172
GenPept AAC36014 AAH02006 AAH27172 BAB25773 BAB26916 BAB27539 BAC25785 BAE26492 BAE41370

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca