Mus musculus Protein: Slc25a24 | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-188338.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Slc25a24 | ||||||||||||
Protein Name | solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24 | ||||||||||||
Synonyms | |||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Protein | ENSMUSP00000029477 | ||||||||||||
InnateDB Gene | IDBG-188336 (Slc25a24) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | Calcium-dependent mitochondrial solute carrier. Mediates the reversible, electroneutral exchange of Mg-ATP or Mg-ADP against phosphate ions, catalyzing the net uptake or efflux of adenine nucleotides across the mitochondrial inner membrane. Nucleotide transport is inactive when cytosolic calcium levels are low, and is activated by an increase in cytosolic calcium levels. May play a role in protecting cells against oxidative stress- induced cell death, probably by promoting the formation of calcium-phosphate precipitates in the mitochondrial matrix, and thereby buffering calcium levels in the mitochondrial matrix (By similarity). {ECO:0000250}. | ||||||||||||
Subcellular Localization | Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | |||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | MGI:1917160 | ||||||||||||
InterPro |
IPR002048
EF-hand domain IPR002067 Mitochondrial carrier protein IPR002167 Graves disease carrier protein IPR018108 Mitochondrial substrate/solute carrier IPR023395 Mitochondrial carrier domain |
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PFAM |
PF00036
PF13202 PF13405 PF00153 |
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PRINTS |
PR00926
PR00928 |
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PIRSF | |||||||||||||
SMART |
SM00054
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TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | Q8BMD8 | ||||||||||||
PhosphoSite | PhosphoSite-Q8BMD8 | ||||||||||||
TrEMBL | Q8R225 | ||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 229731 | ||||||||||||
UniGene | Mm.475563 | ||||||||||||
RefSeq | NP_766273 | ||||||||||||
MGI ID | |||||||||||||
MGI Symbol | Slc25a24 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS17772 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | AK032806 AK146034 AK167778 AK168090 AK170598 AL671921 AL845310 BC022637 BC055369 CT010461 | ||||||||||||
GenPept | AAH22637 AAH55369 BAC28031 BAE26847 BAE39810 BAE40063 BAE41903 CAM19805 CAM26535 CAM28161 | ||||||||||||