Version 5.4
Mus musculus Protein: Gpr18
Summary
InnateDB Protein IDBP-188472.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpr18
Protein Name G protein-coupled receptor 18
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000061410
InnateDB Gene IDBG-188470 (Gpr18)
Protein Structure
UniProt Annotation
Function Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system (By similarity). {ECO:0000250UniProtKB:Q14330}.
Subcellular Localization Cell membrane; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:107859
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K1Z6
PhosphoSite PhosphoSite-Q8K1Z6
TrEMBL
UniProt Splice Variant
Entrez Gene 110168
UniGene Mm.37405
RefSeq NP_877958
MGI ID
MGI Symbol Gpr18
OMIM
CCDS CCDS27342
HPRD
IMGT
EMBL AK156039 AK156868 AK157029 AK172401 BC034872
GenPept AAH34872 BAE33557 BAE33880 BAE33938 BAE42987

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca