Version 5.4
Mus musculus Protein: Idua
Summary
InnateDB Protein IDBP-188493.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Idua
Protein Name iduronidase, alpha-L-
Synonyms 6030426D08;
Species Mus musculus
Ensembl Protein ENSMUSP00000071577
InnateDB Gene IDBG-188491 (Idua)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Lysosome {ECO:0000250}.
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:7698753}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003940 L-iduronidase activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0005102 receptor binding
GO:0005515 protein binding
Biological Process
GO:0000902 cell morphogenesis
GO:0005975 carbohydrate metabolic process
GO:0006027 glycosaminoglycan catabolic process
GO:0007040 lysosome organization
GO:0030209 dermatan sulfate catabolic process
GO:0035108 limb morphogenesis
GO:0048705 skeletal system morphogenesis
GO:0048878 chemical homeostasis
Cellular Component
GO:0005764 lysosome
GO:0030135 coated vesicle
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:96418
InterPro IPR000514 Glycoside hydrolase, family 39
IPR003961 Fibronectin, type III
IPR017853 Glycoside hydrolase, superfamily
PFAM PF01229
PF00041
PF01108
PRINTS PR00745
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48441
PhosphoSite PhosphoSite-
TrEMBL Q8BMG0
UniProt Splice Variant
Entrez Gene 15932
UniGene Mm.358608
RefSeq XP_006534860
MGI ID
MGI Symbol Idua
OMIM
CCDS CCDS19516
HPRD
IMGT
EMBL AC161813 AK031414 L34111
GenPept AAC42044 BAC27393

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca