Version 5.4
Mus musculus Protein: Ntng1
Summary
InnateDB Protein IDBP-188654.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ntng1
Protein Name netrin G1
Synonyms A930010C08Rik; AI853992; Lmnt1;
Species Mus musculus
Ensembl Protein ENSMUSP00000072397
InnateDB Gene IDBG-188652 (Ntng1)
Protein Structure
UniProt Annotation
Function Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites. {ECO:0000269PubMed:11804778}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:10964959}; Lipid-anchor, GPI-anchor {ECO:0000269PubMed:10964959}; Extracellular side {ECO:0000269PubMed:10964959}.
Disease Associations
Tissue Specificity Expression is restricted primarily to neurons of the CNS, particularly in the dorsal thalamus, olfactory bulb and inferior colliculus. Isoform 1A and isoform 1D are the major products in adult brain. {ECO:0000269PubMed:10964959, ECO:0000269PubMed:11804778, ECO:0000269PubMed:11906208}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007409 axonogenesis
Cellular Component
GO:0005886 plasma membrane
GO:0046658 anchored component of plasma membrane
Protein Structure and Domains
PDB ID MGI:1934028
InterPro IPR000742 Epidermal growth factor-like domain
IPR002049 EGF-like, laminin
IPR008211 Laminin, N-terminal
PFAM PF00008
PF00053
PF00055
PRINTS
PIRSF
SMART SM00181
SM00180
SM00136
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R4G0
PhosphoSite PhosphoSite-
TrEMBL F7CVQ1
UniProt Splice Variant
Entrez Gene 80883
UniGene Mm.399954
RefSeq NP_109624
MGI ID
MGI Symbol Ntng1
OMIM
CCDS CCDS38604
HPRD
IMGT
EMBL AB038662 AB038663 AB038664 AB038665 AB038666 AB038667 AC102443 AC102622 AC142115 AF475069 AF475070 AF475071 AF475072 AF475073 AF475074 AF475075 AF475076 AF475077 AF475078 AK034465 AK173075 AL683824 BC079881
GenPept AAH79881 AAL84778 AAL84779 AAL84780 AAL84781 AAL84782 AAL84783 AAL84784 AAL84785 AAL84786 AAL84787 BAB12005 BAB12006 BAB12007 BAB12008 BAB12009 BAB12010 BAC28717 BAD32353

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca