Version 5.4
Mus musculus Protein: Zic5
Summary
InnateDB Protein IDBP-188825.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zic5
Protein Name zinc finger protein of the cerebellum 5
Synonyms 1700049L20Rik; Opr;
Species Mus musculus
Ensembl Protein ENSMUSP00000035754
InnateDB Gene IDBG-188823 (Zic5)
Protein Structure
UniProt Annotation
Function Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA. {ECO:0000269PubMed:15465018}.
Subcellular Localization Nucleus {ECO:0000269PubMed:15465018}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0001843 neural tube closure
GO:0006355 regulation of transcription, DNA-templated
GO:0030154 cell differentiation
GO:0030900 forebrain development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1929518
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TQ40
PhosphoSite PhosphoSite-Q7TQ40
TrEMBL
UniProt Splice Variant
Entrez Gene 65100
UniGene Mm.460864
RefSeq NP_075363
MGI ID
MGI Symbol Zic5
OMIM
CCDS CCDS27348
HPRD
IMGT
EMBL AB042155 AB114214
GenPept BAB18579 BAC79075

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca