InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dpep3

Summary

InnateDB Protein

IDBP-189391.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dpep3

Protein Name

dipeptidase 3

Synonyms

1700018F16Rik; AI507039; MBD-3; MLZ-136;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034371

InnateDB Gene

IDBG-189389 (Dpep3)

Protein Structure

UniProt Annotation

Function

Probable metalloprotease which hydrolyzes cystinyl-bis- glycine. May be involved in meiosis. {ECO:0000269PubMed:20339383}.

Subcellular Localization

Membrane {ECO:0000269PubMed:12738806}; Lipid-anchor, GPI-anchor {ECO:0000269PubMed:12738806}.

Disease Associations

Tissue Specificity

Expressed in testis but not ovary. {ECO:0000269PubMed:12738806, ECO:0000269PubMed:20339383}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0008235	metalloexopeptidase activity
GO:0008239	dipeptidyl-peptidase activity
GO:0016805	dipeptidase activity
GO:0046872	metal ion binding

Biological Process

GO:0006508	proteolysis
GO:0007140	male meiosis

Cellular Component

GO:0016020	membrane
GO:0031225	anchored component of membrane

Protein Structure and Domains

PDB ID

MGI:1919104

InterPro

IPR008257 Renal dipeptidase family

PFAM

PF01244

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9DA79

PhosphoSite

PhosphoSite-Q9DA79

TrEMBL

UniProt Splice Variant

Entrez Gene

71854

UniGene

Mm.173395

RefSeq

NP_082236

MGI ID

MGI Symbol

Dpep3

OMIM

CCDS

CCDS22624

HPRD

IMGT

EMBL

AF488553 AK006085 BC051148

GenPept

AAH51148 AAP84987 BAB24402