Mus musculus Protein: Tfeb
Summary
InnateDB Protein IDBP-189520.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tfeb
Protein Name transcription factor EB
Synonyms bHLHe35; Tcfeb;
Species Mus musculus
Ensembl Protein ENSMUSP00000024786
InnateDB Gene IDBG-189516 (Tfeb)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0046983 protein dimerization activity
Biological Process
GO:0001892 embryonic placenta development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006914 autophagy
GO:0006959 humoral immune response
GO:0007040 lysosome organization
GO:0010508 positive regulation of autophagy
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:103270
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
IPR021802 Basic helix-loop-helix leucine zipper transcrition factor MiT/TFE
PFAM PF00010
PF11851
PRINTS
PIRSF
SMART SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q60982
UniProt Splice Variant
Entrez Gene 21425
UniGene Mm.2305
RefSeq NP_035679
MGI ID
MGI Symbol Tfeb
OMIM
CCDS CCDS28856
HPRD
IMGT
EMBL AC113536 AC124830 AF079095 AK146016 CH466559 U36393
GenPept AAA79697 AAD20979 BAE26834 EDL23584