Version 5.4
Mus musculus Protein: Gjb5
Summary
InnateDB Protein IDBP-189684.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gjb5
Protein Name gap junction protein, beta 5
Synonyms Cnx31.1; Cx31.1; Gjb-5;
Species Mus musculus
Ensembl Protein ENSMUSP00000045325
InnateDB Gene IDBG-189682 (Gjb5)
Protein Structure
UniProt Annotation
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular Localization Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Disease Associations
Tissue Specificity Expressed in skin, much lower in testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007154 cell communication
GO:0060708 spongiotrophoblast differentiation
GO:0060713 labyrinthine layer morphogenesis
Cellular Component
GO:0005922 connexon complex
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:95723
InterPro IPR000500 Connexin
IPR002270 Gap junction beta-4 protein (Cx31.1)
IPR013092 Connexin, N-terminal
IPR019570 Gap junction protein, cysteine-rich domain
PFAM PF00029
PF10582
PRINTS PR00206
PR01141
PIRSF
SMART SM00037
SM01089
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q02739
PhosphoSite PhosphoSite-Q02739
TrEMBL Q542M8
UniProt Splice Variant
Entrez Gene 14622
UniGene Mm.26859
RefSeq NP_034421
MGI ID
MGI Symbol Gjb5
OMIM
CCDS CCDS18670
HPRD
IMGT
EMBL AK082917 CH466552 M91236 M91442
GenPept AAA37426 AAA37427 BAC38687 EDL30251

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca