InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Trem3

Summary

InnateDB Protein

IDBP-189810.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Trem3

Protein Name

triggering receptor expressed on myeloid cells 3

Synonyms

BB134760;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000044478

InnateDB Gene

IDBG-189808 (Trem3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0002374	cytokine secretion involved in immune response
GO:0016477	cell migration
GO:0030593	neutrophil chemotaxis
GO:0042107	cytokine metabolic process
GO:0050755	chemokine metabolic process
GO:0070945	neutrophil mediated killing of gram-negative bacterium
GO:0072672	neutrophil extravasation

Cellular Component

Protein Structure and Domains

PDB ID

MGI:1930003

InterPro

IPR013106 Immunoglobulin V-set domain

PFAM

PF07686

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

MGI ID

MGI Symbol

OMIM

CCDS

HPRD

IMGT

EMBL

AC241601 AF241220 AK079407 BC127035 BC127036 CH466559

GenPept

AAF69835 AAI27036 AAI27037 BAC37636 EDL23603

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca