InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gpr88

Summary

InnateDB Protein

IDBP-189922.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gpr88

Protein Name

G-protein coupled receptor 88

Synonyms

AW061286; Strg;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000087959

InnateDB Gene

IDBG-189920 (Gpr88)

Protein Structure

UniProt Annotation

Function

Orphan receptor.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Expressed almost exclusively in striatum. {ECO:0000269PubMed:11056049}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0004930	G-protein coupled receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007626	locomotory behavior
GO:0019228	neuronal action potential
GO:0050885	neuromuscular process controlling balance

Cellular Component

GO:0005575	cellular_component
GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1927653

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00237

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9EPB7

PhosphoSite

PhosphoSite-

TrEMBL

B2RXU4

UniProt Splice Variant

Entrez Gene

64378

UniGene

Mm.466134

RefSeq

NP_071872

MGI ID

MGI Symbol

Gpr88

OMIM

CCDS

CCDS38610

HPRD

IMGT

EMBL

AB042408 AB042409 BC051941 BC157981 CH466532

GenPept

AAH51941 AAI57982 BAB18245 BAB18246 EDL12386