InnateDB Protein
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IDBP-19036.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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KLRC1
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Protein Name
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killer cell lectin-like receptor subfamily C, member 1
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Synonyms
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CD159A; NKG2; NKG2A;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000256965
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InnateDB Gene
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IDBG-19034 (KLRC1)
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Protein Structure
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Function |
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
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Subcellular Localization |
Membrane; Single-pass type II membrane protein.
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Disease Associations |
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Tissue Specificity |
Natural killer cells.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
6
[view]
|
Protein-Protein |
6
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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|
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Molecular Function |
Accession |
GO Term |
GO:0004888
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transmembrane signaling receptor activity
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GO:0030246
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carbohydrate binding
|
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001304
C-type lectin
IPR008646
Herpesvirus UL45-like
IPR016187
C-type lectin fold
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PFAM |
PF00059
PF05473
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PRINTS |
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PIRSF |
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SMART |
SM00034
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TIGRFAMs |
|
Modification |
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SwissProt |
P26715
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PhosphoSite |
PhosphoSite-P26715
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
3821
|
UniGene |
Hs.512576
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RefSeq |
NP_015567
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HUGO |
HGNC:6374
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OMIM |
161555
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CCDS |
CCDS8626
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HPRD |
01192
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IMGT |
|
EMBL |
AC068775
AF023840
AF461812
BC012550
BC053840
U54783
U54784
U54785
U54786
X54867
X54868
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GenPept |
AAB17133
AAC17488
AAH12550
AAH53840
AAL65234
CAA38649
CAA38650
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