Version 5.4
Mus musculus Protein: Trhde
Summary
InnateDB Protein IDBP-190504.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trhde
Protein Name TRH-degrading enzyme
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000057449
InnateDB Gene IDBG-190502 (Trhde)
Protein Structure
UniProt Annotation
Function Specific inactivation of TRH after its release. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:2384311
InterPro IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal
PFAM PF01433
PRINTS PR00756
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K093
PhosphoSite PhosphoSite-
TrEMBL Q8BZN0
UniProt Splice Variant
Entrez Gene 237553
UniGene Mm.445550
RefSeq NP_666353
MGI ID
MGI Symbol Trhde
OMIM
CCDS CCDS24175
HPRD
IMGT
EMBL AK034093 AK163114 BC032288
GenPept AAH32288 BAC28583 BAE37199

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca