Mus musculus Protein: Fgf6
Summary
InnateDB Protein IDBP-190527.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fgf6
Protein Name fibroblast growth factor 6
Synonyms Fgf-6; HSTF-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000000187
InnateDB Gene IDBG-190525 (Fgf6)
Protein Structure
UniProt Annotation
Function Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration. {ECO:0000250}.
Subcellular Localization Secreted, extracellular space.
Disease Associations
Tissue Specificity Embryos, adult muscles and adult testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005104 fibroblast growth factor receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0001502 cartilage condensation
GO:0001525 angiogenesis
GO:0008284 positive regulation of cell proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0045445 myoblast differentiation
GO:0051781 positive regulation of cell division
Cellular Component
GO:0005615 extracellular space
GO:0042383 sarcolemma
Protein Structure and Domains
PDB ID MGI:95520
InterPro IPR002209 Fibroblast growth factor family
IPR008996 Cytokine, IL-1-like
IPR028142 IL-1 family/FGF family
PFAM
PRINTS PR00263
PR00262
PIRSF
SMART SM00442
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P21658
PhosphoSite PhosphoSite-P21658
TrEMBL
UniProt Splice Variant
Entrez Gene 14177
UniGene Mm.3403
RefSeq NP_034334
MGI ID
MGI Symbol Fgf6
OMIM
CCDS CCDS20561
HPRD
IMGT
EMBL M92415 M92416 X51552
GenPept AAA62260 AAA62261 CAA35925