Version 5.4
Mus musculus Protein: Hscb
Summary
InnateDB Protein IDBP-190604.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hscb
Protein Name HscB iron-sulfur cluster co-chaperone homolog (E. coli)
Synonyms AI325508; AW049829; Hsc20;
Species Mus musculus
Ensembl Protein ENSMUSP00000062811
InnateDB Gene IDBG-190602 (Hscb)
Protein Structure
UniProt Annotation
Function Acts as a co-chaperone in iron-sulfur cluster assembly in mitochondria. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Mitochondrion {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0046872 metal ion binding
GO:0051087 chaperone binding
Biological Process
GO:0006457 protein folding
GO:0016226 iron-sulfur cluster assembly
GO:0051259 protein oligomerization
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005813 centrosome
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:2141135
InterPro IPR001623 DnaJ domain
IPR004640 Co-chaperone Hsc20
IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain
PFAM PF00226
PF07743
PRINTS PR00625
PIRSF
SMART SM00271
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K3A0
PhosphoSite PhosphoSite-Q8K3A0
TrEMBL
UniProt Splice Variant
Entrez Gene 100900
UniGene
RefSeq NP_705799
MGI ID
MGI Symbol Hscb
OMIM
CCDS CCDS51613
HPRD
IMGT
EMBL AK131961 BC027641
GenPept AAH27641 BAE20904

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca