Mus musculus Protein: Mkrn3
Summary
InnateDB Protein IDBP-190619.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mkrn3
Protein Name makorin, ring finger protein, 3
Synonyms D7H15S9-1; Zfp127;
Species Mus musculus
Ensembl Protein ENSMUSP00000091898
InnateDB Gene IDBG-190617 (Mkrn3)
Protein Structure
UniProt Annotation
Function E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in testis, brain, heart and kidney. Ubiquitously detected at low levels throughout the entire embryo, but expression is highest in the ventricular layers of the brain. {ECO:0000269PubMed:10196368, ECO:0000269PubMed:12971993}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
Protein Structure and Domains
PDB ID MGI:2181178
InterPro IPR000571 Zinc finger, CCCH-type
IPR001841 Zinc finger, RING-type
IPR018957 Zinc finger, C3HC4 RING-type
PFAM PF00642
PF13639
PF14634
PF00097
PRINTS
PIRSF
SMART SM00356
SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q60764
PhosphoSite PhosphoSite-Q60764
TrEMBL
UniProt Splice Variant
Entrez Gene 22652
UniGene Mm.146
RefSeq NP_035876
MGI ID
MGI Symbol Mkrn3
OMIM
CCDS CCDS21327
HPRD
IMGT
EMBL AK134870 BC054771 U19106
GenPept AAA76863 AAH54771 BAE22320