Version 5.4
Mus musculus Protein: Sult1c1
Summary
InnateDB Protein IDBP-190982.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sult1c1
Protein Name sulfotransferase family, cytosolic, 1C, member 1
Synonyms (PST)G; mOLFST; P-SULT; ST1C1; Stp2; Sult1a2;
Species Mus musculus
Ensembl Protein ENSMUSP00000024738
InnateDB Gene IDBG-190980 (Sult1c1)
Protein Structure
UniProt Annotation
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). Also shows activity towards cinnamyl alcohol at pH 6.4 but not at pH 5.5, and towards a number of phenolic odorants including eugenol, guaiacol and 2-naphthol. {ECO:0000269PubMed:9560327}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:8641270}.
Disease Associations
Tissue Specificity Expressed only in olfactory tissue. Detected in sustentacular cells in the dorso-medial portion of the nasal cavity. {ECO:0000269PubMed:8641270, ECO:0000269PubMed:9560327}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004027 alcohol sulfotransferase activity
GO:0004062 aryl sulfotransferase activity
GO:0008146 sulfotransferase activity
Biological Process
GO:0006790 sulfur compound metabolic process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:102928
InterPro IPR000863 Sulfotransferase domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00685
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80VR3
PhosphoSite PhosphoSite-Q80VR3
TrEMBL
UniProt Splice Variant
Entrez Gene 20888
UniGene Mm.463237
RefSeq NP_061221
MGI ID
MGI Symbol Sult1c1
OMIM
CCDS CCDS28884
HPRD
IMGT
EMBL AF033653 BC045149
GenPept AAC17740 AAH45149

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca