InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pot1b

Summary

InnateDB Protein

IDBP-191128.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Pot1b

Protein Name

protection of telomeres 1B

Synonyms

2810458H16Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000084089

InnateDB Gene

IDBG-191126 (Pot1b)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0043047	single-stranded telomeric DNA binding

Biological Process

GO:0000723	telomere maintenance
GO:0001558	regulation of cell growth
GO:0007569	cell aging
GO:0016233	telomere capping
GO:0031848	protection from non-homologous end joining at telomere
GO:0043247	telomere maintenance in response to DNA damage
GO:0048239	negative regulation of DNA recombination at telomere
GO:0051276	chromosome organization

Cellular Component

GO:0000783	nuclear telomere cap complex
GO:0000784	nuclear chromosome, telomeric region

Protein Structure and Domains

PDB ID

MGI:1920086

InterPro

IPR011564 Telomeric single stranded DNA binding POT1/Cdc13
IPR012340 Nucleic acid-binding, OB-fold

PFAM

PF02765

PRINTS

PIRSF

SMART

SM00976

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-NP_082646

TrEMBL

H7BX60

UniProt Splice Variant

Entrez Gene

72836

UniGene

RefSeq

NP_082646

MGI ID

MGI Symbol

Pot1b

OMIM

CCDS

CCDS50147

HPRD

IMGT

EMBL

AC154443 AC182748

GenPept