Mus musculus Protein: Emr4
Summary
InnateDB Protein IDBP-191156.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Emr4
Protein Name EGF-like module containing, mucin-like, hormone receptor-like sequence 4
Synonyms D17Ertd479e; Egf-tm7; Fire; Gpr127;
Species Mus musculus
Ensembl Protein ENSMUSP00000025004
InnateDB Gene IDBG-191154 (Emr4)
Protein Structure
UniProt Annotation
Function Could mediated the cellular interaction between myeloid cells and B-cells.
Subcellular Localization Cell membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Predominantly expressed in myeloid cells.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0005509 calcium ion binding
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1196464
InterPro IPR000203 GPS motif
IPR000832 GPCR, family 2, secretin-like
IPR001740 GPCR, family 2, EMR1 hormone receptor
IPR001881 EGF-like calcium-binding domain
IPR017981 GPCR, family 2-like
PFAM PF01825
PF00002
PF07645
PRINTS PR00249
PR01128
PIRSF
SMART SM00303
SM00179
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91ZE5
PhosphoSite PhosphoSite-Q91ZE5
TrEMBL Q0VBQ8
UniProt Splice Variant
Entrez Gene 52614
UniGene Mm.467108
RefSeq NP_631877
MGI ID
MGI Symbol Emr4
OMIM
CCDS CCDS50148
HPRD
IMGT
EMBL AF396935 AK037483 AK155935 AY032690 BC120538 BC120540
GenPept AAI20539 AAI20541 AAK51125 AAL31879 BAC29816 BAE33510