Version 5.4
Mus musculus Protein: Pzp
Summary
InnateDB Protein IDBP-191249.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Pzp
Protein Name pregnancy zone protein
Synonyms A1m; A2m; AI893533; MAM;
Species Mus musculus
Ensembl Protein ENSMUSP00000032510
InnateDB Gene IDBG-191247 (Pzp)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004866 endopeptidase inhibitor activity
GO:0032403 protein complex binding
Biological Process
GO:0007566 embryo implantation
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID MGI:87854
InterPro IPR001599 Alpha-2-macroglobulin
IPR002890 Alpha-2-macroglobulin, N-terminal
IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
IPR009048 Alpha-macroglobulin, receptor-binding
IPR011625 Alpha-2-macroglobulin, N-terminal 2
IPR011626 Alpha-macroglobulin complement component
IPR019565 Alpha-2-macroglobulin, thiol-ester bond-forming
PFAM PF00207
PF01835
PF07677
PF07703
PF07678
PF10569
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3YW52
UniProt Splice Variant
Entrez Gene 11287
UniGene Mm.260144
RefSeq XP_006505442
MGI ID
MGI Symbol Pzp
OMIM
CCDS
HPRD
IMGT
EMBL AC123060
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca