InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc9a9

Summary

InnateDB Protein

IDBP-191301.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc9a9

Protein Name

solute carrier family 9 (sodium/hydrogen exchanger), member 9

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033463

InnateDB Gene

IDBG-191299 (Slc9a9)

Protein Structure

UniProt Annotation

Function

May act in electroneutral exchange of protons for Na(+) across membranes. Involved in the effusion of Golgi luminal H(+) in exchange for cytosolic cations. Involved in organelle ion homeostasis by contributing to the maintenance of the unique acidic pH values of the Golgi and post-Golgi compartments in the cell (By similarity). {ECO:0000250}.

Subcellular Localization

Late endosome membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0015299	solute:proton antiporter activity
GO:0015385	sodium:proton antiporter activity

Biological Process

GO:0006812	cation transport
GO:0006814	sodium ion transport
GO:0006885	regulation of pH
GO:0035725	sodium ion transmembrane transport
GO:0055085	transmembrane transport
GO:1902600	hydrogen ion transmembrane transport