Version 5.4
Mus musculus Protein: Clec2h
Summary
InnateDB Protein IDBP-191538.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Clec2h
Protein Name C-type lectin domain family 2, member h
Synonyms clr-f; Clrf;
Species Mus musculus
Ensembl Protein ENSMUSP00000032518
InnateDB Gene IDBG-191536 (Clec2h)
Protein Structure
UniProt Annotation
Function Lectin-type cell surface receptor. {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Detected in ileum, liver, kidney and in IL2- activated natural killer cells. {ECO:0000269PubMed:11398965}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0030246 carbohydrate binding
GO:0046703 natural killer cell lectin-like receptor binding
Biological Process
GO:0006968 cellular defense response
GO:0007165 signal transduction
Cellular Component
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID MGI:2136934
InterPro IPR001304 C-type lectin
IPR002353 Type-2 ice-structuring protein
IPR016187 C-type lectin fold
PFAM PF00059
PRINTS PR00356
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C1T8
PhosphoSite PhosphoSite-Q8C1T8
TrEMBL
UniProt Splice Variant
Entrez Gene 94071
UniGene Mm.452342
RefSeq NP_444395
MGI ID
MGI Symbol Clec2h
OMIM
CCDS CCDS20576
HPRD
IMGT
EMBL AF350410 AK090364 BC021766
GenPept AAH21766 AAK70358 BAC41184

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca