Version 5.4
Homo sapiens Protein: ATG2B
Summary
InnateDB Protein IDBP-19157.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATG2B
Protein Name ATG2 autophagy related 2 homolog B (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000353010
InnateDB Gene IDBG-19097 (ATG2B)
Protein Structure
UniProt Annotation
Function Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion. {ECO:0000269PubMed:22219374}.
Subcellular Localization Preautophagosomal structure membrane {ECO:0000269PubMed:22219374}; Peripheral membrane protein {ECO:0000269PubMed:22219374}. Lipid droplet {ECO:0000269PubMed:22219374}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000045 autophagic vacuole assembly
GO:0000422 mitochondrion degradation
GO:0006995 cellular response to nitrogen starvation
GO:0044804 nucleophagy
Cellular Component
GO:0000407 pre-autophagosomal structure
GO:0005811 lipid particle
GO:0019898 extrinsic component of membrane
GO:0034045 pre-autophagosomal structure membrane
Protein Structure and Domains
PDB ID
InterPro IPR015412 Autophagy-related, C-terminal
PFAM PF09333
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96BY7
PhosphoSite PhosphoSite-Q96BY7
TrEMBL
UniProt Splice Variant
Entrez Gene 55102
UniGene Hs.623758
RefSeq NP_060506
HUGO HGNC:20187
OMIM
CCDS CCDS9944
HPRD 12626
IMGT
EMBL AK001104 AK055200 AK128275 AL355102 AL359240 BC015016
GenPept AAH15016 BAA91504 BAB70872 BAC87363

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca