Version 5.4
Mus musculus Protein: Pls1
Summary
InnateDB Protein IDBP-191596.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pls1
Protein Name plastin 1 (I-isoform)
Synonyms AI427122;
Species Mus musculus
Ensembl Protein ENSMUSP00000091317
InnateDB Gene IDBG-191592 (Pls1)
Protein Structure
UniProt Annotation
Function Actin-bundling protein in the absence of calcium. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:104809
InterPro IPR001715 Calponin homology domain
IPR002048 EF-hand domain
PFAM PF00307
PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00033
SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3V0K9
PhosphoSite PhosphoSite-Q3V0K9
TrEMBL Q8R0U6
UniProt Splice Variant
Entrez Gene 102502
UniGene Mm.416435
RefSeq NP_001028382
MGI ID
MGI Symbol Pls1
OMIM
CCDS CCDS23412
HPRD
IMGT
EMBL AC091531 AK030875 AK133070 BC026410 BC139068 BC139069 CH466560
GenPept AAH26410 AAI39069 AAI39070 BAE20459 BAE21495 EDL20943

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca