Mus musculus Protein: Plin4
Summary
InnateDB Protein IDBP-191618.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plin4
Protein Name perilipin 4
Synonyms mKIAA1881; S3-12;
Species Mus musculus
Ensembl Protein ENSMUSP00000002908
InnateDB Gene IDBG-191616 (Plin4)
Protein Structure
UniProt Annotation
Function May play a role in triacylglycerol packaging into adipocytes. May function as a coat protein involved in the biogenesis of lipid droplets. {ECO:0000269PubMed:12840023, ECO:0000269PubMed:15731108}.
Subcellular Localization Cell membrane. Cytoplasm. Lipid droplet. Note=Nascent lipid droplet surface-associated; association with lipid droplets is triacylglycerol synthesis-dependent.
Disease Associations
Tissue Specificity Specifically expressed in white adipose tissue and also weakly detected in heart and skeletal muscle (at protein level). {ECO:0000269PubMed:12840023, ECO:0000269PubMed:15111493, ECO:0000269PubMed:9624692}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005811 lipid particle
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:1929709
InterPro IPR004279 Perilipin
PFAM PF03036
PRINTS
PIRSF PIRSF036881
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O88492
PhosphoSite PhosphoSite-O88492
TrEMBL
UniProt Splice Variant
Entrez Gene 57435
UniGene Mm.12966
RefSeq
MGI ID
MGI Symbol Plin4
OMIM
CCDS
HPRD
IMGT
EMBL AF064748 AK080156 AK173286 CT009719
GenPept AAC23666 BAC37834 BAD32564