Version 5.4
Mus musculus Protein: Clec12a
Summary
InnateDB Protein IDBP-191886.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Clec12a
Protein Name C-type lectin domain family 12, member a
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000063627
InnateDB Gene IDBG-191884 (Clec12a)
Protein Structure
UniProt Annotation
Function Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. {ECO:0000250}.
Subcellular Localization Cell membrane; Single-pass type II membrane protein. Note=Ligand binding leads to internalization. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0019903 protein phosphatase binding
GO:0030246 carbohydrate binding
Biological Process
GO:0050776 regulation of immune response
Cellular Component
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3040968
InterPro IPR001304 C-type lectin
IPR016187 C-type lectin fold
PFAM PF00059
PRINTS
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q504P2
PhosphoSite PhosphoSite-Q504P2
TrEMBL I3QI48
UniProt Splice Variant
Entrez Gene 232413
UniGene Mm.90241
RefSeq NP_808354
MGI ID
MGI Symbol Clec12a
OMIM
CCDS CCDS20584
HPRD
IMGT
EMBL AC138620 AK084335 BC094904 JX026279
GenPept AAH94904 AFK08678 BAC39163

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca