InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Coro1c

Summary

InnateDB Protein

IDBP-191931.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Coro1c

Protein Name

coronin, actin binding protein 1C

Synonyms

AL022675; AW455561; AW548837;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000004646

InnateDB Gene

IDBG-191929 (Coro1c)

Protein Structure

UniProt Annotation

Function

May be involved in cytokinesis, motility, and signal transduction. {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000250}. Cell projection, lamellipodium. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Localize in a diffuse and punctate pattern in the cytosol and are highly enriched in F-actin-rich areas. {ECO:0000250}.

Disease Associations

Tissue Specificity

Ubiquitous.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0051015	actin filament binding

Biological Process

GO:0000147	actin cortical patch assembly
GO:0006909	phagocytosis
GO:0030036	actin cytoskeleton organization

Cellular Component

GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0015629	actin cytoskeleton
GO:0030027	lamellipodium

Protein Structure and Domains

PDB ID

MGI:1345964

InterPro

IPR001680 WD40 repeat
IPR015048 Domain of unknown function DUF1899
IPR015049 Domain of unknown function DUF1900
IPR017986 WD40-repeat-containing domain

PFAM

PF00400
PF08953
PF08954

PRINTS

PIRSF

SMART

SM00320

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9WUM4