Version 5.4
Mus musculus Protein: Lass3
Summary
InnateDB Protein IDBP-191991.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lass3
Protein Name LAG1 homolog, ceramide synthase 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000069238
InnateDB Gene IDBG-191989 (Lass3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0050291 sphingosine N-acyltransferase activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0030148 sphingolipid biosynthetic process
GO:0030216 keratinocyte differentiation
GO:0046513 ceramide biosynthetic process
Cellular Component
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID MGI:2681008
InterPro IPR001356 Homeobox domain
IPR006634 TRAM/LAG1/CLN8 homology domain
IPR009057 Homeodomain-like
IPR016439 Longevity assurance, LAG1/LAC1
PFAM PF00046
PF03798
PRINTS
PIRSF PIRSF005225
SMART SM00389
SM00724
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q1A3B0
PhosphoSite PhosphoSite-Q1A3B0
TrEMBL
UniProt Splice Variant
Entrez Gene 545975
UniGene Mm.490603
RefSeq NP_001157673
MGI ID
MGI Symbol Cers3
OMIM
CCDS CCDS52268
HPRD
IMGT
EMBL AC120791 DQ358087 DQ646881
GenPept ABC87758 ABG00152

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca