Version 5.4
Mus musculus Protein: Klre1
Summary
InnateDB Protein IDBP-192088.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Klre1
Protein Name killer cell lectin-like receptor family E member 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000055779
InnateDB Gene IDBG-192086 (Klre1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0019903 protein phosphatase binding
GO:0030246 carbohydrate binding
GO:0042803 protein homodimerization activity
GO:0046983 protein dimerization activity
Biological Process
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002859 negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0030101 natural killer cell activation
GO:0032729 positive regulation of interferon-gamma production
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
Protein Structure and Domains
PDB ID MGI:2662547
InterPro IPR001304 C-type lectin
IPR016187 C-type lectin fold
PFAM PF00059
PRINTS
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8CJC7
UniProt Splice Variant
Entrez Gene 243655
UniGene
RefSeq NP_705818
MGI ID
MGI Symbol Klre1
OMIM
CCDS CCDS20589
HPRD
IMGT
EMBL AC161602 AF306663
GenPept AAN31172

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca