Version 5.4
Mus musculus Protein: Spem1
Summary
InnateDB Protein IDBP-192132.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Spem1
Protein Name sperm maturation 1
Synonyms 1700095G12Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000037500
InnateDB Gene IDBG-192130 (Spem1)
Protein Structure
UniProt Annotation
Function Required for proper cytoplasm removal during spermatogenesis. {ECO:0000269PubMed:17426145}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269PubMed:17426145}.
Disease Associations
Tissue Specificity Testis-specific. Exclusively present in cytoplasm of steps 14-16 elongated spermatids (at protein level). {ECO:0000269PubMed:17426145}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007283 spermatogenesis
GO:0007291 sperm individualization
GO:0030317 sperm motility
Cellular Component
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1921538
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5F289
PhosphoSite PhosphoSite-Q5F289
TrEMBL
UniProt Splice Variant
Entrez Gene 74288
UniGene
RefSeq NP_083131
MGI ID
MGI Symbol Spem1
OMIM
CCDS CCDS36199
HPRD
IMGT
EMBL AK007080 AL603707 BC100505 EF120626
GenPept AAI00506 ABO33756 BAB24854 CAI51963

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca